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Research ArticleOriginal Article
Open Access

Prevalence of thyroid disorders among the diabetic population in Arar, Saudi Arabia

Haider O. Elmisbah, Riyad Y. Laham, Hafiz O. Almisbah, Hadeel T. Alanazi, Taif A. Alanazi, Raghad M. Alanzi, Wejdan A. Aldahmashi, Anshoo Agarwal and Rashad Q. Othman
Saudi Medical Journal June 2024, 45 (6) 591-597; DOI: https://doi.org/10.15537/smj.2024.45.6.20240144
Haider O. Elmisbah
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
MRCS, MD
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  • ORCID record for Haider O. Elmisbah
  • For correspondence: [email protected]
Riyad Y. Laham
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
MD
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Hafiz O. Almisbah
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
MD
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Hadeel T. Alanazi
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
Roles: Medical student
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Taif A. Alanazi
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
Roles: Medical student
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Raghad M. Alanzi
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
Roles: Medical student
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Wejdan A. Aldahmashi
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
Roles: Medical student
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Anshoo Agarwal
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
MD
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Rashad Q. Othman
From the Department of General Surgery(Elmisbah, Laham); from the Department of Internal Medicine(Almisbah); from the Department of Pathology (Agarwal, Othman), Faculty of Medicine; and from the College of Medicine (T. Alanazi, A. Alanazi, Alanzi, Aldahmashi), Northern Border University, Arar, Kingdom of Saudi Arabia.
MD, PhD
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Article Figures & Data

Tables

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    Table 1

    - Sociodemographic characteristics of the participants (N=411).

    Parametersn (%)
    Age
    18-2026 (6.3)
    20-35150 (36.5)
    35-4058 (14.1)
    40-4583 (20.2)
    50-5558 (14.1)
    60>36 (8.8)
    Nationality
    Saudi402 (97.8)
    Non-Saudi9 (2.2)
    No25 (6.1)
    Education level
    Uneducated38 (9.2)
    Basic5 (1.2)
    Primary17 (4.1)
    Middle24 (5.8)
    Secondary77 (18.7)
    Bachelor’s degree226 (55.0)
    Above university16 (3.9)
    Others8 (1.9)
    Occupation
    Businessman19 (4.6)
    Factor17 (4.1)
    Military2 (0.5)
    Employee167 (40.6)
    Student25 (6.1)
    retired6 (1.5)
    Housewife22 (5.4)
    not working133 (32.4)
    Other20 (4.9)
    Marital status
    Married258 (62.8)
    Single120 (29.2)
    Divorced17 (4.1)
    Widowed16 (3.9)
    Duration of thyroid disorder
    Less than one year56 (13.6)
    1-5 years42 (10.2)
    more than 5 years40 (9.7)
    Do not have thyroid disease273 (66.4)
    Overweight or obese
    Yes188 (45.7)
    No223 (54.3)
    BMI
    Underweight7 (1.7)
    Normal139 (33.8)
    Obese135 (32.8)
    Overweight130 (31.6)
    Waist circumference (cm)
    less than 707 (1.7)
    70-100110 (26.8)
    100-140119 (29.0)
    140-180112 (27.3)
    Do not know63 (15.3)
    • Values are presented as numbers and percentages (%). BMI: body mass index

    • View popup
    Table 2

    - Comorbid diseases among the study participants (N=411).

    Parametersn (%)
    Comorbid diseases (bias risk)
    Vitamin D deficiency174 (42.3)
    Vitamin B12 deficiency108 (26.3)
    Hypertension91 (22.1)
    High blood lipids43 (10.5)
    Iron deficiency anemia60 (14.6)
    Diabetes5 (1.2)
    Nothing23 (5.6)
    Have diabetes
    Yes176 (42.8)
    No235 (57.2)
    Type of diabetes (n= 176)
    The first type57 (32.4)
    The second type119 (67.6)
    • Values are presented as numbers and percentages (%).

    • View popup
    Table 3

    - Participants’ knowledge regarding thyroid disorders in diabetes mellitus patients (N=411).

    Manifestations of thyroid disordersYesNoNeutral
    Hypothyroidism affects the level of cholesterol in the blood224 (54.5)79 (19.2)108 (26.3)
    A weak thyroid gland leads to heart disease209 (50.9)90 (21.9)112 (27.3)
    Is there a relationship between diabetes and thyroid disorders?211 (51.3)96 (23.4)104 (25.3)
    Is hypothyroidism hereditary?179 (43.6)143 (34.8)89 (21.7)
    Fatigue and drowsiness are symptoms of thyroid disorders305 (74.2)47 (11.4)59 (14.4)
    Sudden weight gain is a symptom of thyroid disorders308 (74.9)47 (11.4)56 (13.6)
    Dry skin and hair are symptoms of thyroid disorders267 (65.0)64 (15.6)80 (19.5)
    Did you know that thyroid disorders are associated with serious outcomes for the mother and fetus, when left untreated?268 (65.2)78 (19.0)65 (15.8)
    Did you know that thyroid disorder is linked to iodine deficiency?227 (55.2)97 (23.6)87 (21.2)
    Did you know that thyroid disorders can occur when taking certain medications or after undergoing surgery?211 (51.3)110 (26.8)90 (21.9)
    The association between diabetes mellitus and thyroid disorders results from several biochemical, genetic, and hormonal malfunctions.195 (47.4)82 (20.0)134 (32.6)
    Diabetes and thyroid disorders have similar signs and symptoms, such as edema, fatigue, paleness, and weight gain.251 (61.1)69 (16.8)91 (22.1)
    The combination of diabetes and thyroid disorders can mask early diabetes complications195 (47.4)85 (20.7)131 (31.9)
    Diabetes treatment can worsen thyroid disorder148 (36.0)115 (28.0)148 (36.0)
    Antithyroid medications can worsen blood sugar control174 (42.3)84 (20.4)153 (37.2)
    Diabetes affects thyroid function by altering the level of thyroid hormone and impairing the conversion of thyroid hormone to triiodothyronine in peripheral tissues.190 (46.2)63 (15.3)158 (38.4)
    The effectiveness of thyroid hormone therapy may be affected in hypothyroid patients with coexisting diabetes175 (42.6)77 (18.7)159 (38.7)
    There may be an increased incidence of differentiated thyroid cancer among women with diabetes171 (41.6)84 (20.4)156 (38.0)
    Medications taken for diabetes, thyroid disorder, and other comorbidities can alter thyroid function or blood sugar control in people who live with diabetes and thyroid disorder.184 (44.8)70 (17.0)157 (38.2)
    An unrecognized thyroid disorder can worsen blood sugar control and increase cardiovascular risks in diabetes.188 (45.7)72 (17.5)151 (36.7)
    The effect of thyroid hormone in the digestive tract is to increase glucose absorption181 (44.0)77 (18.7)153 (37.2)
    The effect of thyroid hormone on the liver: increased gluconeogenesis in the liver176 (42.8)75 (18.2)160 (38.9)
    The effect of thyroid hormone on adipose tissue is to increase lipolysis, increase fatty acids in plasma.179 (43.6)71 (17.3)161 (39.2)
    The effect of thyroid hormone on muscles is to increase glucose uptake181 (44.0)70 (17.0)160 (38.9)
    The effect of thyroid hormone on pancreatic beta cells is to increase insulin secretion187 (45.5)71 (17.3)153 (37.2)
    • Values are presented as numbers and percentages (%).

    • View popup
    Table 4

    - Association between the presence and duration of thyroid disease and the presence of diabetes mellitus and waist circumference (N=411).

    VariablesThyroid presence and durationTotal (N=411)P-values
    Less than one yearFrom 1-5 yearsMore than 5 yearsNo
    Waist circumference (cm)
    less than 700 (0.0)2 (0.5)0 (0.0)5 (1.2)7 (1.7)0.670
    70-10017 (4.1)9 (2.2)8 (1.9)76 (18.5)110 (26.8)
    100-14014 (3.4)12 (2.9)12 (2.9)81 (19.7)119 (29.0)
    140-18017 (4.1)15 (3.6)12 (2.9)68 (16.5)112 (27.3)
    I do not know8 (1.9)4 (1.0)8 (1.9)43 (10.5)63 (15.3)
    Have DM?
    Yes29 (7.1)22 (5.4)15 (3.6)110 (26.8)176 (42.8)0.205
    No27 (6.6)20 (4.9)25 (6.1)163 (39.7)235 (57.2)
    • Values are presented as numbers and percentages (%). T-test used to calculate the p-values.

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Saudi Medical Journal: 45 (6)
Saudi Medical Journal
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1 Jun 2024
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Prevalence of thyroid disorders among the diabetic population in Arar, Saudi Arabia
Haider O. Elmisbah, Riyad Y. Laham, Hafiz O. Almisbah, Hadeel T. Alanazi, Taif A. Alanazi, Raghad M. Alanzi, Wejdan A. Aldahmashi, Anshoo Agarwal, Rashad Q. Othman
Saudi Medical Journal Jun 2024, 45 (6) 591-597; DOI: 10.15537/smj.2024.45.6.20240144

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Prevalence of thyroid disorders among the diabetic population in Arar, Saudi Arabia
Haider O. Elmisbah, Riyad Y. Laham, Hafiz O. Almisbah, Hadeel T. Alanazi, Taif A. Alanazi, Raghad M. Alanzi, Wejdan A. Aldahmashi, Anshoo Agarwal, Rashad Q. Othman
Saudi Medical Journal Jun 2024, 45 (6) 591-597; DOI: 10.15537/smj.2024.45.6.20240144
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Keywords

  • goitre
  • hyperthyroidism
  • hypothyroidism
  • diabetes mellitus
  • hyperglycaemia

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