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Research ArticleOriginal Article
Open Access

Evaluation of haemoglobin constant spring phenotypes and their haematological characteristics among high school students in Terengganu, Malaysia

A single - centred study

Sharifatul F. Embong, Sumaiyah Adzahar, Adibah Daud, Mohammad H. Nordin, Sarah A. Halim, Wan Zuhairah W. Embong, Nabilah Rameli, Razan H. Zulkeflee and Rosnah Bahar
Saudi Medical Journal March 2025, 46 (3) 292-298; DOI: https://doi.org/10.15537/smj.2025.46.3.20240771
Sharifatul F. Embong
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
BS
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Sumaiyah Adzahar
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
MD, MPATH
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  • ORCID record for Sumaiyah Adzahar
  • For correspondence: [email protected]
Adibah Daud
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
MBBS, MPATH
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Mohammad H. Nordin
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
MBBS, MMED
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Sarah A. Halim
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
MBBS, MPATH
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Wan Zuhairah W. Embong
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
MBBS, MPATH
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Nabilah Rameli
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
MBBS, MPATH
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Razan H. Zulkeflee
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
MD, MPATH
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Rosnah Bahar
From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
MD, MPATH
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Article Information

vol. 46 no. 3 292-298
DOI 
https://doi.org/10.15537/smj.2025.46.3.20240771

Published By 
Saudi Medical Journal
Online ISSN 
1658-3175
History 
  • Received September 8, 2024
  • Accepted February 18, 2025
  • Published online March 17, 2025.

Copyright & Usage 
Copyright: © Saudi Medical Journal This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

Author Information

  1. Sharifatul F. Embong, BS,
  2. Sumaiyah Adzahar, MD, MPATH⇑,
  3. Adibah Daud, MBBS, MPATH,
  4. Mohammad H. Nordin, MBBS, MMED,
  5. Sarah A. Halim, MBBS, MPATH,
  6. Wan Zuhairah W. Embong, MBBS, MPATH,
  7. Nabilah Rameli, MBBS, MPATH,
  8. Razan H. Zulkeflee, MD, MPATH and
  9. Rosnah Bahar, MD, MPATH
  1. From the Department of Pathology and Medical Laboratory (F. Embong, Adzahar, Daud), Faculty of Medicine, Sultan Zainal Abidin University, from the Department of Pathology (W. Embong), Sultanah Nur Zahirah Hospital, from the Department of Pathology (Rameli), Dungun Hospital, Terengganu, from the Department of Pathology and Laboratory Medicine (Halim), College of Medicine, International Islamic University Malaysia, Pahang, and from the Department of Haematology (Zulkeflee, Bahar), School of Medical Sciences, University of Science Malaysia, Kelantan, Malaysia.
  1. Address correspondence and reprint request to: Dr. Sumaiyah Adzahar, Department of Pathology and Medical Laboratory, Faculty of Medicine, Sultan Zainal Abidin University, Terengganu, Malaysia. E-mail: srikandimaya11{at}gmail.com
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Evaluation of haemoglobin constant spring phenotypes and their haematological characteristics among high school students in Terengganu, Malaysia
Sharifatul F. Embong, Sumaiyah Adzahar, Adibah Daud, Mohammad H. Nordin, Sarah A. Halim, Wan Zuhairah W. Embong, Nabilah Rameli, Razan H. Zulkeflee, Rosnah Bahar
Saudi Medical Journal Mar 2025, 46 (3) 292-298; DOI: 10.15537/smj.2025.46.3.20240771

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Evaluation of haemoglobin constant spring phenotypes and their haematological characteristics among high school students in Terengganu, Malaysia
Sharifatul F. Embong, Sumaiyah Adzahar, Adibah Daud, Mohammad H. Nordin, Sarah A. Halim, Wan Zuhairah W. Embong, Nabilah Rameli, Razan H. Zulkeflee, Rosnah Bahar
Saudi Medical Journal Mar 2025, 46 (3) 292-298; DOI: 10.15537/smj.2025.46.3.20240771
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Keywords

  • alpha thalassemia
  • haemoglobin constant spring
  • high performance liquid chromatography
  • capillary electrophoresis

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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