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Research ArticleOriginal Article
Open Access

Impact of acute kidney injury on long-term mortality and progression to chronic kidney disease among critically ill children

Najlaa G. Al-Otaibi, Maryam Zeinelabdin, Mohamed A. Shalaby, Norah Khathlan, Ghadi D. Mashat, Amal A. Zahrani, Sundus MW. NoorSaeed, Nora M. Shalabi, Khalid A. Alhasan, Sara N. Sharief, Amr S. Albanna and Jameela A. Kari
Saudi Medical Journal February 2017, 38 (2) 138-142; DOI: https://doi.org/10.15537/smj.2017.2.16012
Najlaa G. Al-Otaibi
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
MBChB, SB-Ped
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Maryam Zeinelabdin
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
MBChB, SB-Ped
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Mohamed A. Shalaby
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
MBBS, MSC
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Norah Khathlan
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
CABP, SB-ped
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Ghadi D. Mashat
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
Medical Student
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Amal A. Zahrani
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
Medical Student
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Sundus MW. NoorSaeed
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
Medical Student
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Nora M. Shalabi
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
Medical Student
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Khalid A. Alhasan
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
SSC-Ped, KSUF
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Sara N. Sharief
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
Medical Student
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Amr S. Albanna
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
MD, MSc
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Jameela A. Kari
From the Pediatric Nephrology Center of Excellence (Al-Otaibi, Zeinelabdin, Shalaby M, Mashat, Zahrani, NoorSaeed, Shalaby N, Sharief, Kari), Intensive Care Unit (Khathlan), Department of Pediatrics, King Abdulaziz University, King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and Department of Pediatrics (Alhasan), King Saud University, Riyadh, Kingdom of Saudi Arabia
MD, FRCP
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  • For correspondence: [email protected] [email protected]
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    Figure 1

    Kaplan-Meier curve showing survival rate among patients admitted to pediatric intensive care unit with renal impairment

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    Figure 2

    Kaplan-meier curve showing survival rate among patients admitted to pediatric intensive care unit stratified by the extent of renal impairment, based on pediatric risk, injury, failure, loss, and end-stage renal disease (pRIFLE).

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    Figure 3

    Glomerular filtration rate level during 2 years follow-up among patients with normal versus high (30 mg/dl or more) urine protein level at baseline.

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    Figure 4

    Glomerular filtration rate level during 2 years follow-up after admission to pediatric intensive care unit, stratified by the modified pediatric risk, injury, failure, loss, and end-stage renal disease criteria at the time of admission.

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Saudi Medical Journal: 38 (2)
Saudi Medical Journal
Vol. 38, Issue 2
1 Feb 2017
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Impact of acute kidney injury on long-term mortality and progression to chronic kidney disease among critically ill children
Najlaa G. Al-Otaibi, Maryam Zeinelabdin, Mohamed A. Shalaby, Norah Khathlan, Ghadi D. Mashat, Amal A. Zahrani, Sundus MW. NoorSaeed, Nora M. Shalabi, Khalid A. Alhasan, Sara N. Sharief, Amr S. Albanna, Jameela A. Kari
Saudi Medical Journal Feb 2017, 38 (2) 138-142; DOI: 10.15537/smj.2017.2.16012

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Impact of acute kidney injury on long-term mortality and progression to chronic kidney disease among critically ill children
Najlaa G. Al-Otaibi, Maryam Zeinelabdin, Mohamed A. Shalaby, Norah Khathlan, Ghadi D. Mashat, Amal A. Zahrani, Sundus MW. NoorSaeed, Nora M. Shalabi, Khalid A. Alhasan, Sara N. Sharief, Amr S. Albanna, Jameela A. Kari
Saudi Medical Journal Feb 2017, 38 (2) 138-142; DOI: 10.15537/smj.2017.2.16012
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