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Research ArticleOriginal Article
Open Access

Remifentanil consumption in septoplasty surgery under general anesthesia

Association with humane mu-opioid receptor gene variants

Mahmoud M. Al-Mustafa, Abdelkarim S. Al Oweidi, Khaled R. Al-Zaben, Ibraheem Y. Qudaisat, Sami A. Abu-Halaweh, Subhi M. Al-Ghanem, Islam M. Massad, Walid K. Samarah, Reem A. Al-Shaer and Said I. Ismail
Saudi Medical Journal February 2017, 38 (2) 170-175; DOI: https://doi.org/10.15537/smj.2017.2.16348
Mahmoud M. Al-Mustafa
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD, FACHARZT
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  • For correspondence: [email protected]
Abdelkarim S. Al Oweidi
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD
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Khaled R. Al-Zaben
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD
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Ibraheem Y. Qudaisat
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD
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Sami A. Abu-Halaweh
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD
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Subhi M. Al-Ghanem
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD
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Islam M. Massad
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD
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Walid K. Samarah
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD
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Reem A. Al-Shaer
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
BSc
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Said I. Ismail
From the Department of Anesthesia and Intensive Care (Al-Mustafa, Al Oweidi, Al-Zaben, Qudaisat, Abu-Halaweh, Al-Ghanem, Massad, Samarah), Jordan University Hospital, Department of Biochemistry and Physiology (Al-Shaer, Ismail), Faculty of Medicine, The University of Jordan, Amman, Jordan
MD
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    Figure 1

    Representative polymerase chain reaction (PCR) products for A118G genotype. Lane1 is a 100 bp ladder, lane 2 shows non-template controls, while lanes 3 to 6 represent the PCR products (293 bp).

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    Figure 2

    Heart rate (HR) variation over 70 minutes (m) after induction of general anesthesia for the codon 118 genotype.

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    Figure 3

    Systolic blood pressure (SBP) variation over 70 minutes after induction of general anesthesia for the codon 118 genotype.

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Saudi Medical Journal: 38 (2)
Saudi Medical Journal
Vol. 38, Issue 2
1 Feb 2017
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Remifentanil consumption in septoplasty surgery under general anesthesia
Mahmoud M. Al-Mustafa, Abdelkarim S. Al Oweidi, Khaled R. Al-Zaben, Ibraheem Y. Qudaisat, Sami A. Abu-Halaweh, Subhi M. Al-Ghanem, Islam M. Massad, Walid K. Samarah, Reem A. Al-Shaer, Said I. Ismail
Saudi Medical Journal Feb 2017, 38 (2) 170-175; DOI: 10.15537/smj.2017.2.16348

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Remifentanil consumption in septoplasty surgery under general anesthesia
Mahmoud M. Al-Mustafa, Abdelkarim S. Al Oweidi, Khaled R. Al-Zaben, Ibraheem Y. Qudaisat, Sami A. Abu-Halaweh, Subhi M. Al-Ghanem, Islam M. Massad, Walid K. Samarah, Reem A. Al-Shaer, Said I. Ismail
Saudi Medical Journal Feb 2017, 38 (2) 170-175; DOI: 10.15537/smj.2017.2.16348
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