Micro-RNA-21 rs1292037 A&gt;G polymorphism can predict hepatocellular carcinoma prognosis (HCC), and plays a key role in cell proliferation and ischemia-reperfusion injury (IRI) in HCC cell model of IRI

Chaoyu Wu; Gongen Tang; Xiaoying Wang; Jian Zhang; Shuhua Chen; Cuihong Lu; Dongqin Zhang; Yun Li

doi:10.15537/smj.2020.4.24994

References

↵
1. Torre LA,
2. Bray F,
3. Siegel RL,
4. Ferlay J,
5. Lortet-Tieulent J,
6. Jemal A
(2015) Global cancer statistics 2012. CA Cancer J Clin 65:87–108.
OpenUrl CrossRef PubMed
↵
1. Sia D,
2. Villanueva A,
3. Friedman SL,
4. Llovet JM
(2017) Liver cancer cell of origin, molecular class, and effects on patient prognosis. Gastroenterology 152:745–761.
OpenUrl CrossRef PubMed
↵
1. Yao C,
2. Li G,
3. Cai M,
4. Qian Y,
5. Wang L,
6. Xiao L,
7. et al.
(2017) Expression and genetic polymorphism of necroptosis related protein RIPK1 is correlated with severe hepatic ischemia-reperfusion injury and prognosis after hepatectomy in hepatocellular carcinoma patients. Cancer Biomark 20:23–29.
OpenUrl
↵
1. Murakami Y,
2. Tanahashi T,
3. Okada R,
4. Toyoda H,
5. Kumada T,
6. Enomoto M,
7. et al.
(2014) Comparison of hepatocellular carcinoma miRNA expression profiling as evaluated by next generation sequencing and microarray. PLoS One 9:e106314.
OpenUrl
↵
1. Xie Y,
2. Yao Q,
3. Butt AM,
4. Guo J,
5. Tian Z,
6. Bao X,
7. et al.
(2014) Expression profiling of serum microRNA-101 in HBV-associated chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Cancer Biol Ther 15:1248–1255.
OpenUrl
↵
1. Moszyńska A,
2. Gebert M,
3. Collawn JF,
4. Bartoszewski R
(2017) SNPs in microRNA target sites and their potential role in human disease. Open Biol 7:170019.
OpenUrl CrossRef PubMed
↵
1. Han BW,
2. Li ZH,
3. Liu SF,
4. Han HB,
5. Dong SJ,
6. Zou HJ,
7. et al.
(2016) A comprehensive review of microRNA-related polymorphisms in gastric cancer. Genet Mol Res 15:1–10.
OpenUrl CrossRef
↵
1. Papaconstantinou I,
2. Kapizioni C,
3. Legaki E,
4. Xourgia E,
5. Karamanolis G,
6. Gklavas A,
7. et al.
(2017) Association of miR-146 rs2910164, miR-196a rs11614913, miR-221 rs113054794 and miR-224 rs188519172 polymorphisms with anti-TNF treatment response in a Greek population with Crohn's disease. World J Gastrointest Pharmacol Ther 8:193–200.
OpenUrl
↵
1. Ge Y,
2. Zhang L,
3. Nikolova M,
4. Reva B,
5. Fuchs E
(2016) Strand-specific in vivo screen of cancer-associated miRNAs unveils a role for miR-21(?) in SCC progression. Nat Cell Biol 18:111–121.
OpenUrl
↵
1. Ma X,
2. Conklin DJ,
3. Li F,
4. Dai Z,
5. Hua X,
6. Li Y,
7. et al.
(2015) The oncogenic microRNA miR-21 promotes regulated necrosis in mice. Nat Commun 6:7151.
OpenUrl CrossRef PubMed
↵
1. Wu C,
2. Wang X,
3. Zhang J,
4. Tang G,
5. Xu Y,
6. Lu C,
7. Li Y
(2019) MicroRNA-224 expression and polymorphism predict the prognosis of hepatitis B virus-related hepatocellular carcinoma patients after liver resection. Clin Lab, 65.
↵
1. Ding W,
2. Yang H,
3. Gong S,
4. Shi W,
5. Xiao J,
6. Gu J,
7. et al.
(2017) Candidate miRNAs and pathogenesis investigation for hepatocellular carcinoma based on bioinformatics analysis. Oncol Lett 13:3409–3414.
OpenUrl
↵
1. Jiang X,
2. Lew KS,
3. Chen Q,
4. Richards AM,
5. Wang P
(2018) Human mesenchymal stem cell-derived exosomes reduce ischemia/reperfusion injury by the inhibitions of apoptosis and autophagy. Curr Pharm Des 24:5334–5341.
OpenUrl
↵
1. Xu HX,
2. Pan W,
3. Qian JF,
4. Liu F,
5. Dong HQ,
6. Liu QJ
(2019) MicroRNA 21 contributes to the puerarin induced cardioprotection via suppression of apoptosis and oxidative stress in a cell model of ischemia/reperfusion injury. Mol Med Rep 20:719–727.
OpenUrl
↵
1. Zucman-Rossi J,
2. Villanueva A,
3. Nault JC,
4. Llovet JM
(2015) Genetic landscape and biomarkers of hepatocellular carcinoma. Gastroenterology 149:1226–1239.
OpenUrl CrossRef PubMed
↵
1. Mathew S,
2. Abdel-Hafiz H,
3. Raza A,
4. Fatima K,
5. Qadri I
(2016) Host nucleotide polymorphism in hepatitis B virus-associated hepatocellular carcinoma. World J Hepatol 8:485–498.
OpenUrl
↵
1. Petrini E,
2. Caviglia GP,
3. Abate ML,
4. Fagoonee S,
5. Smedile A,
6. Pellicano R
(2015) MicroRNAs in HBV-related hepatocellular carcinoma:functions and potential clinical applications. Panminerva Med 57:201–209.
OpenUrl PubMed
↵
1. Li X,
2. Wu X
(2018) MiR-21-5p promotes the progression of non-small-cell lung cancer by regulating the expression of SMAD7. Onco Targets Ther 11:8445–8454.
OpenUrl
1. Han Z,
2. Chen Y,
3. Zhang Y,
4. Wei A,
5. Zhou J,
6. Li Q,
7. et al.
(2017) MiR-21/PTEN axis promotes skin wound healing by dendritic cells enhancement. J Cell Biochem 118:3511–3519.
OpenUrl
↵
1. Qiu YF,
2. Wang MX,
3. Meng LN,
4. Zhang R,
5. Wang W
(2018) MiR-21 regulates proliferation and apoptosis of oral cancer cells through TNF-? Eur Rev Med Pharmacol Sci 22:7735–7741.
OpenUrl
↵
1. Zhuang C,
2. Jiang W,
3. Huang D,
4. Xu L,
5. Yang Q,
6. Zheng L,
7. et al.
(2016) Serum miR-21, miR-26a and miR-101 as potential biomarkers of hepatocellular carcinoma. Clin Res Hepatol Gastroenterol 40:386–396.
OpenUrl
↵
1. Huang CS,
2. Yu W,
3. Cui H,
4. Wang YJ,
5. Zhang L,
6. Han F,
7. et al.
(2015) Increased expression of miR-21 predicts poor prognosis in patients with hepatocellular carcinoma. Int J Clin Exp Pathol 8:7234–7238.
OpenUrl
↵
1. Yi PS,
2. Li JS
(2018) High expression of miR-21 is not a predictor of poor prognosis in all patients with hepatocellular carcinoma. Mol Clin Oncol 8:733–739.
OpenUrl
↵
1. Wang SM,
2. Zeng WX,
3. Wu WS,
4. Sun LL,
5. Yan D
(2018) Association between a microRNA binding site polymorphism in SLCO1A2 and the risk of delayed methotrexate elimination in Chinese children with acute lymphoblastic leukemia. Leuk Res 65:61–66.
OpenUrl
↵
1. Shi L,
2. Lin H,
3. Li G,
4. Jin RA,
5. Xu J,
6. Sun Y,
7. et al.
(2016) Targeting androgen receptor (AR)?IL12A signal enhances efficacy of sorafenib plus NK cells immunotherapy to better suppress HCC progression. Mol Cancer Ther 15:731–742.
OpenUrl Abstract/FREE Full Text
↵
1. Karababa A,
2. Groos-Sahr K,
3. Albrecht U,
4. Keitel V,
5. Shafigullina A,
6. Görg B,
7. Häussinger D
(2017) Ammonia Attenuates LPS-Induced Upregulation of Pro-Inflammatory Cytokine mRNA in Co-Cultured Astrocytes and Microglia. Neurochem Res 42:737–749.
OpenUrl
↵
1. Zhang CY,
2. Yuan WG,
3. He P,
4. Lei JH,
5. Wang CX
(2016) Liver fibrosis and hepatic stellate cells:Etiology, pathological hallmarks and therapeutic targets. World J Gastroenterol 22:10512–10522.
OpenUrl CrossRef

In this issue

Download PDF

Email Article

Citation Tools

Bookmark this article

Cited By...

No citing articles found.

Google Scholar

More in this TOC Section

Show more Original Article

Keywords

[1] ↵
Torre LA,
Bray F,
Siegel RL,
Ferlay J,
Lortet-Tieulent J,
Jemal A
(2015) Global cancer statistics 2012. CA Cancer J Clin 65:87–108.
OpenUrl CrossRef PubMed

[2] Torre LA,

[3] Bray F,

[4] Siegel RL,

[5] Ferlay J,

[6] Lortet-Tieulent J,

[7] Jemal A

[8] ↵
Sia D,
Villanueva A,
Friedman SL,
Llovet JM
(2017) Liver cancer cell of origin, molecular class, and effects on patient prognosis. Gastroenterology 152:745–761.
OpenUrl CrossRef PubMed

[9] Sia D,

[10] Villanueva A,

[11] Friedman SL,

[12] Llovet JM

[13] ↵
Yao C,
Li G,
Cai M,
Qian Y,
Wang L,
Xiao L,
et al.
(2017) Expression and genetic polymorphism of necroptosis related protein RIPK1 is correlated with severe hepatic ischemia-reperfusion injury and prognosis after hepatectomy in hepatocellular carcinoma patients. Cancer Biomark 20:23–29.
OpenUrl

[14] Yao C,

[15] Li G,

[16] Cai M,

[17] Qian Y,

[18] Wang L,

[19] Xiao L,

[20] et al.

[21] ↵
Murakami Y,
Tanahashi T,
Okada R,
Toyoda H,
Kumada T,
Enomoto M,
et al.
(2014) Comparison of hepatocellular carcinoma miRNA expression profiling as evaluated by next generation sequencing and microarray. PLoS One 9:e106314.
OpenUrl

[22] Murakami Y,

[23] Tanahashi T,

[24] Okada R,

[25] Toyoda H,

[26] Kumada T,

[27] Enomoto M,

[28] et al.

[29] ↵
Xie Y,
Yao Q,
Butt AM,
Guo J,
Tian Z,
Bao X,
et al.
(2014) Expression profiling of serum microRNA-101 in HBV-associated chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Cancer Biol Ther 15:1248–1255.
OpenUrl

[30] Xie Y,

[31] Yao Q,

[32] Butt AM,

[33] Guo J,

[34] Tian Z,

[35] Bao X,

[36] et al.

[37] ↵
Moszyńska A,
Gebert M,
Collawn JF,
Bartoszewski R
(2017) SNPs in microRNA target sites and their potential role in human disease. Open Biol 7:170019.
OpenUrl CrossRef PubMed

[38] Moszyńska A,

[39] Gebert M,

[40] Collawn JF,

[41] Bartoszewski R

[42] ↵
Han BW,
Li ZH,
Liu SF,
Han HB,
Dong SJ,
Zou HJ,
et al.
(2016) A comprehensive review of microRNA-related polymorphisms in gastric cancer. Genet Mol Res 15:1–10.
OpenUrl CrossRef

[43] Han BW,

[44] Li ZH,

[45] Liu SF,

[46] Han HB,

[47] Dong SJ,

[48] Zou HJ,

[49] et al.

[50] ↵
Papaconstantinou I,
Kapizioni C,
Legaki E,
Xourgia E,
Karamanolis G,
Gklavas A,
et al.
(2017) Association of miR-146 rs2910164, miR-196a rs11614913, miR-221 rs113054794 and miR-224 rs188519172 polymorphisms with anti-TNF treatment response in a Greek population with Crohn's disease. World J Gastrointest Pharmacol Ther 8:193–200.
OpenUrl

[51] Papaconstantinou I,

[52] Kapizioni C,

[53] Legaki E,

[54] Xourgia E,

[55] Karamanolis G,

[56] Gklavas A,

[57] et al.

[58] ↵
Ge Y,
Zhang L,
Nikolova M,
Reva B,
Fuchs E
(2016) Strand-specific in vivo screen of cancer-associated miRNAs unveils a role for miR-21(?) in SCC progression. Nat Cell Biol 18:111–121.
OpenUrl

[59] Ge Y,

[60] Zhang L,

[61] Nikolova M,

[62] Reva B,

[63] Fuchs E

[64] ↵
Ma X,
Conklin DJ,
Li F,
Dai Z,
Hua X,
Li Y,
et al.
(2015) The oncogenic microRNA miR-21 promotes regulated necrosis in mice. Nat Commun 6:7151.
OpenUrl CrossRef PubMed

[65] Ma X,

[66] Conklin DJ,

[67] Li F,

[68] Dai Z,

[69] Hua X,

[70] Li Y,

[71] et al.

[72] ↵
Wu C,
Wang X,
Zhang J,
Tang G,
Xu Y,
Lu C,
Li Y
(2019) MicroRNA-224 expression and polymorphism predict the prognosis of hepatitis B virus-related hepatocellular carcinoma patients after liver resection. Clin Lab, 65.

[73] Wu C,

[74] Wang X,

[75] Zhang J,

[76] Tang G,

[77] Xu Y,

[78] Lu C,

[79] Li Y

[80] ↵
Ding W,
Yang H,
Gong S,
Shi W,
Xiao J,
Gu J,
et al.
(2017) Candidate miRNAs and pathogenesis investigation for hepatocellular carcinoma based on bioinformatics analysis. Oncol Lett 13:3409–3414.
OpenUrl

[81] Ding W,

[82] Yang H,

[83] Gong S,

[84] Shi W,

[85] Xiao J,

[86] Gu J,

[87] et al.

[88] ↵
Jiang X,
Lew KS,
Chen Q,
Richards AM,
Wang P
(2018) Human mesenchymal stem cell-derived exosomes reduce ischemia/reperfusion injury by the inhibitions of apoptosis and autophagy. Curr Pharm Des 24:5334–5341.
OpenUrl

[89] Jiang X,

[90] Lew KS,

[91] Chen Q,

[92] Richards AM,

[93] Wang P

[94] ↵
Xu HX,
Pan W,
Qian JF,
Liu F,
Dong HQ,
Liu QJ
(2019) MicroRNA 21 contributes to the puerarin induced cardioprotection via suppression of apoptosis and oxidative stress in a cell model of ischemia/reperfusion injury. Mol Med Rep 20:719–727.
OpenUrl

[95] Xu HX,

[96] Pan W,

[97] Qian JF,

[98] Liu F,

[99] Dong HQ,

[100] Liu QJ

[101] ↵
Zucman-Rossi J,
Villanueva A,
Nault JC,
Llovet JM
(2015) Genetic landscape and biomarkers of hepatocellular carcinoma. Gastroenterology 149:1226–1239.
OpenUrl CrossRef PubMed

[102] Zucman-Rossi J,

[103] Villanueva A,

[104] Nault JC,

[105] Llovet JM

[106] ↵
Mathew S,
Abdel-Hafiz H,
Raza A,
Fatima K,
Qadri I
(2016) Host nucleotide polymorphism in hepatitis B virus-associated hepatocellular carcinoma. World J Hepatol 8:485–498.
OpenUrl

[107] Mathew S,

[108] Abdel-Hafiz H,

[109] Raza A,

[110] Fatima K,

[111] Qadri I

[112] ↵
Petrini E,
Caviglia GP,
Abate ML,
Fagoonee S,
Smedile A,
Pellicano R
(2015) MicroRNAs in HBV-related hepatocellular carcinoma:functions and potential clinical applications. Panminerva Med 57:201–209.
OpenUrl PubMed

[113] Petrini E,

[114] Caviglia GP,

[115] Abate ML,

[116] Fagoonee S,

[117] Smedile A,

[118] Pellicano R

[119] ↵
Li X,
Wu X
(2018) MiR-21-5p promotes the progression of non-small-cell lung cancer by regulating the expression of SMAD7. Onco Targets Ther 11:8445–8454.
OpenUrl

[120] Li X,

[121] Wu X

[122] Han Z,
Chen Y,
Zhang Y,
Wei A,
Zhou J,
Li Q,
et al.
(2017) MiR-21/PTEN axis promotes skin wound healing by dendritic cells enhancement. J Cell Biochem 118:3511–3519.
OpenUrl

[123] Han Z,

[124] Chen Y,

[125] Zhang Y,

[126] Wei A,

[127] Zhou J,

[128] Li Q,

[129] et al.

[130] ↵
Qiu YF,
Wang MX,
Meng LN,
Zhang R,
Wang W
(2018) MiR-21 regulates proliferation and apoptosis of oral cancer cells through TNF-? Eur Rev Med Pharmacol Sci 22:7735–7741.
OpenUrl

[131] Qiu YF,

[132] Wang MX,

[133] Meng LN,

[134] Zhang R,

[135] Wang W

[136] ↵
Zhuang C,
Jiang W,
Huang D,
Xu L,
Yang Q,
Zheng L,
et al.
(2016) Serum miR-21, miR-26a and miR-101 as potential biomarkers of hepatocellular carcinoma. Clin Res Hepatol Gastroenterol 40:386–396.
OpenUrl

[137] Zhuang C,

[138] Jiang W,

[139] Huang D,

[140] Xu L,

[141] Yang Q,

[142] Zheng L,

[143] et al.

[144] ↵
Huang CS,
Yu W,
Cui H,
Wang YJ,
Zhang L,
Han F,
et al.
(2015) Increased expression of miR-21 predicts poor prognosis in patients with hepatocellular carcinoma. Int J Clin Exp Pathol 8:7234–7238.
OpenUrl

[145] Huang CS,

[146] Yu W,

[147] Cui H,

[148] Wang YJ,

[149] Zhang L,

[150] Han F,

[151] et al.

[152] ↵
Yi PS,
Li JS
(2018) High expression of miR-21 is not a predictor of poor prognosis in all patients with hepatocellular carcinoma. Mol Clin Oncol 8:733–739.
OpenUrl

[153] Yi PS,

[154] Li JS

[155] ↵
Wang SM,
Zeng WX,
Wu WS,
Sun LL,
Yan D
(2018) Association between a microRNA binding site polymorphism in SLCO1A2 and the risk of delayed methotrexate elimination in Chinese children with acute lymphoblastic leukemia. Leuk Res 65:61–66.
OpenUrl

[156] Wang SM,

[157] Zeng WX,

[158] Wu WS,

[159] Sun LL,

[160] Yan D

[161] ↵
Shi L,
Lin H,
Li G,
Jin RA,
Xu J,
Sun Y,
et al.
(2016) Targeting androgen receptor (AR)?IL12A signal enhances efficacy of sorafenib plus NK cells immunotherapy to better suppress HCC progression. Mol Cancer Ther 15:731–742.
OpenUrl Abstract/FREE Full Text

[162] Shi L,

[163] Lin H,

[164] Li G,

[165] Jin RA,

[166] Xu J,

[167] Sun Y,

[168] et al.

[169] ↵
Karababa A,
Groos-Sahr K,
Albrecht U,
Keitel V,
Shafigullina A,
Görg B,
Häussinger D
(2017) Ammonia Attenuates LPS-Induced Upregulation of Pro-Inflammatory Cytokine mRNA in Co-Cultured Astrocytes and Microglia. Neurochem Res 42:737–749.
OpenUrl

[170] Karababa A,

[171] Groos-Sahr K,

[172] Albrecht U,

[173] Keitel V,

[174] Shafigullina A,

[175] Görg B,

[176] Häussinger D

[177] ↵
Zhang CY,
Yuan WG,
He P,
Lei JH,
Wang CX
(2016) Liver fibrosis and hepatic stellate cells:Etiology, pathological hallmarks and therapeutic targets. World J Gastroenterol 22:10512–10522.
OpenUrl CrossRef

[178] Zhang CY,

[179] Yuan WG,

[180] He P,

[181] Lei JH,

[182] Wang CX

Main menu

User menu

Search

Micro-RNA-21 rs1292037 A>G polymorphism can predict hepatocellular carcinoma prognosis (HCC), and plays a key role in cell proliferation and ischemia-reperfusion injury (IRI) in HCC cell model of IRI

References

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Keywords

CONTENT

JOURNAL

AUTHORS

Main menu

User menu

Search

Micro-RNA-21 rs1292037 A>G polymorphism can predict hepatocellular carcinoma prognosis (HCC), and plays a key role in cell proliferation and ischemia-reperfusion injury (IRI) in HCC cell model of IRI

References

In this issue

Citation Manager Formats

Jump to section

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Keywords

CONTENT

JOURNAL

AUTHORS