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Glutathione and oxidized nicotinamide adenine dinucleotide (NAD+) redox status in plasma and placental tissue of Saudi patients with intrauterine growth restriction

Feda S. Aljaser, Hazem K. Ghneim, Mashael M. ALshubaily, Manal Abudawood, Faisal Almajed, Sabiha Fatima and Yazeed A. ALsheikh
Saudi Medical Journal May 2021, 42 (5) 491-498; DOI: https://doi.org/10.15537/smj.2021.42.5.20200685

References

  1. 1.↵
    1. Copel J,
    2. D`Alton M,
    3. Feltovich M,
    4. Gratacos E,
    5. Karkow D,
    6. Odibo A,
    7. Platt L,
    8. Tutschek B
    1. Magriples U.
    Intrauterine growth restriction. Fetal Diagnosis and Care. In: Copel J, D`Alton M, Feltovich M, Gratacos E, Karkow D, Odibo A, Platt L, Tutschek B, editors. Obstetric Imaging. 2nd ed. Philadelphia: Elsevier; 2018. p. 466–472.
  2. 2.↵
    1. Pantham P,
    2. Rosario F,
    3. Weintraub S,
    4. Nathanielsz P,
    5. Powell T,
    6. Li C, et al.
    Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in maternal nutrient restricted baboons. Biol Reprod 2016; 95: 1–9.
    OpenUrlCrossRefPubMed
  3. 3.↵
    1. Almutairy SF,
    2. Binhazzaa AM,
    3. Bukhari ME,
    4. Al-Shaikh GK,
    5. AlMandeel HM.
    A comparison of the etiology of early versus late fetal death from a single center. Int J of Advanced App Sciences 2019; 6: 30–34.
    OpenUrl
  4. 4.↵
    1. Sferruzzi-Perri AN,
    2. Higgins JS,
    3. Vaughan OR,
    4. Murray AJ,
    5. Fowden AL.
    Placental mitochondria adapt developmentally and in response to hypoxia to support fetal growth. PNAS 2019; 116: 1621–1626.
    OpenUrlAbstract/FREE Full Text
  5. 5.↵
    1. Ghneim HK,
    2. Alshebly MM.
    Biochemical markers of oxidative stress in Saudi women with recurrent miscarriage. J Korean med science 2016; 31: 98–105.
    OpenUrl
  6. 6.↵
    1. Zhang J,
    2. Wang X,
    3. Vikash V,
    4. Ye Q,
    5. Wu D,
    6. Liu Y,
    7. Dong W.
    ROS and ROS-mediated cellular signalling. Oxidative Med Cell Longevity 2016; 4350965, 18.
    OpenUrl
  7. 7.↵
    1. Zygula A,
    2. Kosinski P,
    3. Wroczynski P,
    4. Makarewicz-Wujec M,
    5. Pietrzak B,
    6. Wielgos M, et al.
    Oxidative stress markers differ in two placental dysfunction pathologies: pregnancy-induced hypertension and intrauterine growth restriction. Oxid Med Cell Longevity 2020; 2020: 1323891.
    OpenUrl
  8. 8.↵
    1. Al-Sheikh YA,
    2. Ghneim HK,
    3. Alharbi AF,
    4. Alshebly MM,
    5. Aljaser FS,
    6. Aboul-Soud MAM.
    Molecular and biochemical investigations of key antioxidant/oxidant molecules in Saudi patients with recurrent miscarriage. Exp Ther Med 2019; 18: 4450–4460.
    OpenUrl
  9. 9.↵
    1. Khan S,
    2. Khan S,
    3. Khan MM,
    4. Alam R,
    5. Khan A.
    Estimation of the status of MDA levels and SOD activity in pregnant women. Biochem Cell Arch 2019; 19: 169–173.
    OpenUrl
  10. 10.↵
    1. Mehdi M,
    2. Menon MK,
    3. Seyoum N,
    4. Bekele M,
    5. Tigeneh W,
    6. Seifu D.
    Blood and tissue enzymatic activities of GDH and LDH, index of glutathione, and oxidative stress among breast cancer patients attending Referral Hospitals of Addis Ababa, Ethiopia: hospital-based comparative cross-sectional study. Oxid Med Cell Longev 2018; 2018: 6039453.
    OpenUrl
  11. 11.↵
    1. Hayashi M,
    2. Takahashi K,
    3. Tamura J.
    Enhanced dihydroflavnol-4-reductase activity and NAD homeostasis leading to cell death tolerance in transgenic mice. Proc Natl Acad Sci U S A 2005; 102: 7020–7025.
    OpenUrlAbstract/FREE Full Text
  12. 12.↵
    1. Ghneim HK,
    2. Al Sheikh YA,
    3. Alshebly MM,
    4. Aboul-Soud MA.
    Superoxide dismutase activity and gene expression levels in Saudi women with recurrent miscarriage. Mol Med Rep 2016; 13: 2606–2612.
    OpenUrl
  13. 13.↵
    1. Ishii T,
    2. Yasuda K,
    3. Miyazawa M,
    4. Mitsushita J,
    5. Johnson TE,
    6. Hartman PS,
    7. Ishii N.
    Infertility and recurrent miscarriage with complex II deficiency dependent mitochondrial oxidative stress in animal models. Mech Ageing Dev 2016; 155: 22–35.
    OpenUrl
  14. 14.↵
    1. Yung HW,
    2. Calabrese S,
    3. Hynx D,
    4. Hemmings BA,
    5. Cetin I,
    6. Charnock-Jones DS, et al.
    Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction. Am J Pathol 2008; 173: 451–462.
    OpenUrlCrossRefPubMedWeb of Science
  15. 15.↵
    1. Zhao RZ,
    2. Jiang S,
    3. Zhang L,
    4. Yu ZB.
    Mitochondrial electron transport chain, ROS generation and uncoupling (Review). Int J Mol Med 2019; 44: 3–15.
    OpenUrlCrossRef
  16. 16.↵
    1. Singh Arpita,
    2. Ambujam K.
    Maternal socio-demographic determinants and fetal outcome of intrauterine growth restriction. Int J Rep Contracep Obst Gynecol 2018; 7: 3843–384.
    OpenUrl
  17. 17.↵
    1. Malhotra A,
    2. Allison BJ,
    3. Castillo-Melendez M,
    4. Jenkin G,
    5. Polglase GR,
    6. Miller SL.
    Neonatal morbidities of fetal growth restriction: pathophysiology and impact. Front Endocrinol (Lausanne) 2019; 10: 55.
    OpenUrl
  18. 18.↵
    1. Zur RL,
    2. Kingdom JC,
    3. Parks WT,
    4. Hobson SR.
    The placental basis of fetal growth restriction. Obstet Gynecol Clin North Am 2020; 47: 81–98.
    OpenUrlCrossRefPubMed
  19. 19.↵
    1. Sharma D,
    2. Shastri S,
    3. Sharma P.
    Intrauterine growth restriction: antenatal and postnatal aspects. Clin Med Insights Pediatr 2016; 14: 67–83.
    OpenUrl
  20. 20.↵
    1. Menon R,
    2. Mesiano S,
    3. Taylor RN.
    Programmed fetal membrane senescence and exosome-mediated signaling: a mechanism associated with timing of human parturition. Front Endocrinol 2017; 8: 196.
    OpenUrl
  21. 21.↵
    1. Menon R.
    Initiation of human parturition: signaling from senescent fetal tissues via extracellular vesicle mediated paracrine mechanism. Obstet Gynecol Sci 2019; 62: 199–211.
    OpenUrl
  22. 22.↵
    1. Tomin T,
    2. Schittmayer M,
    3. Birner-Gruenberger R.
    Addressing glutathione redox status in clinical samples by two-step alkylation with n-ethylmaleimide isotopologues. Metabolites 2020; 10: 71.
    OpenUrl
  23. 23.↵
    1. Abudawood M,
    2. Tabassum H,
    3. Almaarik B,
    4. Aljohi A.
    Interrelationship between oxidative stress, DNA damage and cancer risk in diabetes (Type 2) in Riyadh, KSA. Saudi J Biol Sci 2020; 27: 177–183.
    OpenUrl
  24. 24.↵
    1. Rashid CS,
    2. Bansal A,
    3. Simmons RA.
    Oxidative stress, intrauterine growth restriction, and developmental programming of type 2 diabetes. Physiology (Bethesda) 2018; 1; 33: 348–359.
    OpenUrl
  25. 25.↵
    1. Hracsko Z,
    2. Orvos H,
    3. Novak Z,
    4. Pal A,
    5. Varga IS.
    Evaluation of oxidative stress markers in neonates with intra-uterine growth retardation. Redox Rep 2018; 13: 11–16.
    OpenUrl
  26. 26.↵
    1. Malpica G,
    2. Pinero S,
    3. Chiarello DI,
    4. Proverbio F,
    5. Marín R,
    6. Abad C.
    IUGR, lipid peroxidation, and calcium ATPase activity of maternal red blood cell ghosts. J Pregnancy Reprod 2017; 1: 1–5.
    OpenUrl
  27. 27.↵
    1. Xie N,
    2. Zhang L,
    3. Gao W,
    4. Huang C,
    5. Huber PE,
    6. Zhou X, et al.
    NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential. Sig Transduct Target Ther 2020; 5: 227.
    OpenUrl
  28. 28.↵
    1. Katsyuba E,
    2. Mottis A,
    3. Zietak M,
    4. De Franco F,
    5. van der Velpen V,
    6. Gariani K, et al.
    De novo NAD+ synthesis enhances mitochondrial function and improves health. Nature 2018; 563: 354–359.
    OpenUrlCrossRefPubMed
  29. 29.↵
    1. Goody MF,
    2. Henry CA.
    A need for NAD+ in muscle development, homeostasis, and aging. Skeletal Muscle 2018; 8: 9.
    OpenUrl
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