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Case ReportCase Report
Open Access

Kaposi’s sarcoma associated with adult dermatomyositis

Khawla K. Alghanim and Batol G. Gasmelseed
Saudi Medical Journal May 2021, 42 (5) 570-573; DOI: https://doi.org/10.15537/smj.2021.42.5.20200583
Khawla K. Alghanim
From the Rheumatology Unit, Internal Medicine Department (Alghanim), and from the Internal Medicine Department (Gasmelseed), King Fahad Medical Military Complex, Dhahran, Kingdom of Saudi Arabia.
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Batol G. Gasmelseed
From the Rheumatology Unit, Internal Medicine Department (Alghanim), and from the Internal Medicine Department (Gasmelseed), King Fahad Medical Military Complex, Dhahran, Kingdom of Saudi Arabia.
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    Figure 1

    - Appearance of multiple violaceous oval and round macules and plaques on the patient’s face and upper limbs.

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    Table 1

    - Laboratory data at diagnosis of dermatomyositis and at 2 months post-treatment.

    ParametersAt the time of diagnosisTwo months after treatmentReference range
    Hematology   
    Hgb (g/dl)12.513.913-18
    WBC (103/µl)3.414.24-11
    Lymphocytes (103/µl)0.8101.41.5-4
    Platelets (103/µl)99193150-450
    Chemistry
    Creatinine (µmol/L)696171-115
    BUN (mmol/L)4.672.5-6.4
    CK96973039-308
    AST5172715-37
    Serum troponin0.1302-<0.026
    Albumin (g/L)203634-50
    Serology
    ANA (homogeneous)1:320-Negative
    Anti-Mi-2NegativeNegative
    Anti-Jo-1NegativeNegative
    Anti-RNPNegativeNegative
    Anti-ds-DNANegative-Negative
    HIV (ELISA)NegativeNegative
    CRP410.5<6
    ESR1810<15 (male)
    24-Hour urinary albumin<0.300-<0.300
    Tumor markers
    Total PSA (ng /ml)2.10-4
    CA19-9 (U/mL)<7.760-37
    CEA (ng/mL)1.980-5
    Hgb: hemoglobin, WBC: white blood cell, BUN: blood urea nitrogen, CK: creatinine kinase, AST: aspartate aminotransferase,ANA: antinuclear antibody, CRP: C-reactive protein, ESR: erythrocyte sedimentation rate
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    Table 2

    - Timeline of the outcomes of our patient from the initial visit to the treatment and follow-up visits.

    DateHistory/intervention/outcomes
    November 22, 2018Presented to the emergency room with proximal myopathy, skin rashes, and dysphagia. He was admitted to the medical ward
    November 23, 2018Magnetic resonance imaging of the thighs, electromyography, pulse therapy of intravenous methylprednisolone at a dose of 1 g once daily for 3 days
    November 24, 2018Muscle biopsy
    November 26, 2018Oral prednisolone at a dose of 60 mg once daily
    November 27, 2018Discharge home
    December 9, 2018Oral azathioprine at a dose of 50 mg once daily
    December 15, 2018Free from symptoms with normalization of muscle enzyme levels
    December 21, 2018New skin lesions appeared; thus, azathioprine was discontinued. Oral prednisolone was titrated until 5 mg once daily, and skin biopsy was performed
    January 1, 2019Chemotherapy started (a total of 16 sessions)
    November 30, 2019There were no more skin lesions and no muscle weakness; thus, prednisolone was discontinued gradually
    August 30, 2020In the follow-up assessment at the rheumatology clinic, physical examination and blood test showed normal findings
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Saudi Medical Journal: 42 (5)
Saudi Medical Journal
Vol. 42, Issue 5
1 May 2021
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Kaposi’s sarcoma associated with adult dermatomyositis
Khawla K. Alghanim, Batol G. Gasmelseed
Saudi Medical Journal May 2021, 42 (5) 570-573; DOI: 10.15537/smj.2021.42.5.20200583

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Kaposi’s sarcoma associated with adult dermatomyositis
Khawla K. Alghanim, Batol G. Gasmelseed
Saudi Medical Journal May 2021, 42 (5) 570-573; DOI: 10.15537/smj.2021.42.5.20200583
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Keywords

  • dermatomyositis
  • Kaposi’s sarcoma
  • dysphagia
  • inflammatory myopathy

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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