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Review ArticleReview Article
Open Access

An overview of pathophysiology and treatment options of osteonecrosis of femoral head in sickle cell disease

Mohammed L. Al-Otaibi
Saudi Medical Journal November 2022, 43 (11) 1192-1199; DOI: https://doi.org/10.15537/smj.2022.43.11.20220429
Mohammed L. Al-Otaibi
From theDepartment of Orthopedic Surgery, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.
MD, FRCSC
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Saudi Medical Journal
Vol. 43, Issue 11
1 Nov 2022
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An overview of pathophysiology and treatment options of osteonecrosis of femoral head in sickle cell disease
Mohammed L. Al-Otaibi
Saudi Medical Journal Nov 2022, 43 (11) 1192-1199; DOI: 10.15537/smj.2022.43.11.20220429

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An overview of pathophysiology and treatment options of osteonecrosis of femoral head in sickle cell disease
Mohammed L. Al-Otaibi
Saudi Medical Journal Nov 2022, 43 (11) 1192-1199; DOI: 10.15537/smj.2022.43.11.20220429
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  • Article
    • Abstract
    • Osteonecrosis of the femoral head in SCD
    • Prevalence of ONFH
    • Etiology and causative factors for ONFH
    • Pathophysiology
    • Classification systems for ONFH diagnosis
    • Therapeutic approaches for ONFH
    • Novel treatment approaches
    • Cell therapies
    • Conclusion
    • Acknowledgment
    • Footnotes
    • References
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Keywords

  • sickle cell disease
  • osteonecrosis of the femoral head
  • pathophysiology
  • treatment options
  • hyperbaric oxygen
  • cell therapies
  • core decompression
  • bone grafting
  • osteotomy
  • total hip arthroplasty

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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