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Review ArticleReview Article
Open Access

An overview of pathophysiology and treatment options of osteonecrosis of femoral head in sickle cell disease

Mohammed L. Al-Otaibi
Saudi Medical Journal November 2022, 43 (11) 1192-1199; DOI: https://doi.org/10.15537/smj.2022.43.11.20220429
Mohammed L. Al-Otaibi
From theDepartment of Orthopedic Surgery, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.
MD, FRCSC
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An overview of pathophysiology and treatment options of osteonecrosis of femoral head in sickle cell disease
Mohammed L. Al-Otaibi
Saudi Medical Journal Nov 2022, 43 (11) 1192-1199; DOI: 10.15537/smj.2022.43.11.20220429

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An overview of pathophysiology and treatment options of osteonecrosis of femoral head in sickle cell disease
Mohammed L. Al-Otaibi
Saudi Medical Journal Nov 2022, 43 (11) 1192-1199; DOI: 10.15537/smj.2022.43.11.20220429
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  • Article
    • Abstract
    • Osteonecrosis of the femoral head in SCD
    • Prevalence of ONFH
    • Etiology and causative factors for ONFH
    • Pathophysiology
    • Classification systems for ONFH diagnosis
    • Therapeutic approaches for ONFH
    • Novel treatment approaches
    • Cell therapies
    • Conclusion
    • Acknowledgment
    • Footnotes
    • References
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Keywords

  • sickle cell disease
  • osteonecrosis of the femoral head
  • pathophysiology
  • treatment options
  • hyperbaric oxygen
  • cell therapies
  • core decompression
  • bone grafting
  • osteotomy
  • total hip arthroplasty

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