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Research ArticleOriginal Article
Open Access

Synergistic efficacies of thymoquinone and standard antibiotics against multi-drug resistant isolates

Ayed A. Dera, Irfan Ahmad, Prasanna Rajagopalan, Mesfer Al Shahrani, Ahmed Saif, Mohammad Y. Alshahrani, Yasser Alraey, Ahmad M. Alamri, Sultan Alasmari, Mohammed Makkawi, Ali G. Alkhathami, Gaffar Zaman, Abdulrahim Hakami, Razan Alhefzi and Mohammad A. Alfhili
Saudi Medical Journal February 2021, 42 (2) 196-204; DOI: https://doi.org/10.15537/smj.2021.2.25706
Ayed A. Dera
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Irfan Ahmad
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Prasanna Rajagopalan
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Mesfer Al Shahrani
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Ahmed Saif
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Mohammad Y. Alshahrani
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Yasser Alraey
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Ahmad M. Alamri
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Sultan Alasmari
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Mohammed Makkawi
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Ali G. Alkhathami
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Gaffar Zaman
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Abdulrahim Hakami
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Razan Alhefzi
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Mohammad A. Alfhili
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Article Information

vol. 42 no. 2 196-204
DOI 
https://doi.org/10.15537/smj.2021.2.25706
PubMed 
33563739

Published By 
Saudi Medical Journal
Online ISSN 
1658-3175
History 
  • Received November 14, 2020
  • Accepted January 14, 2021
  • Published online February 9, 2021.

Copyright & Usage 
Copyright: © Saudi Medical Journal This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Information

  1. Ayed A. Dera, PhD,
  2. Irfan Ahmad, PhD,
  3. Prasanna Rajagopalan, PhD,
  4. Mesfer Al Shahrani, PhD,
  5. Ahmed Saif, PhD,
  6. Mohammad Y. Alshahrani, PhD,
  7. Yasser Alraey, PhD,
  8. Ahmad M. Alamri, PhD,
  9. Sultan Alasmari, PhD,
  10. Mohammed Makkawi, PhD,
  11. Ali G. Alkhathami, PhD,
  12. Gaffar Zaman, MD,
  13. Abdulrahim Hakami, PhD,
  14. Razan Alhefzi, MSc and
  15. Mohammad A. Alfhili, PhD
  1. From the Department of Clinical Laboratory Sciences, Central Research Laboratory (Dera, Ahmad, Rajagopalan, Al Shahrani, Alshahrani, Alraey, Alamri, Alasmari, Makkawi, Alkhathami, Zaman, Hakami, Alhefzi), College of Applied Medical Sciences, King Khalid University, and From the Department of Clinical Laboratory Sciences, Central Research Laboratory (AlAmri), College of Applied Medical Sciences, and Cancer Research Unit, King Khalid University, Abha; from the Department of Clinical Laboratory Sciences (Saif), College of Applied Medical Sciences, Najran University, Najran; and the Chair of Medical and Molecular Genetics Research, Department of Clinical Laboratory Sciences (Alfhili), College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
  1. Address correspondence and reprint request to: Dr. Ayed A. Dera, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Kingdom of Saudi Arabia. E-mail: ayedd{at}kku.edu.sa ORCID ID: https://orcid.org/0000-0002-6248-8983
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Saudi Medical Journal: 42 (2)
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Synergistic efficacies of thymoquinone and standard antibiotics against multi-drug resistant isolates
Ayed A. Dera, Irfan Ahmad, Prasanna Rajagopalan, Mesfer Al Shahrani, Ahmed Saif, Mohammad Y. Alshahrani, Yasser Alraey, Ahmad M. Alamri, Sultan Alasmari, Mohammed Makkawi, Ali G. Alkhathami, Gaffar Zaman, Abdulrahim Hakami, Razan Alhefzi, Mohammad A. Alfhili
Saudi Medical Journal Feb 2021, 42 (2) 196-204; DOI: 10.15537/smj.2021.2.25706

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Synergistic efficacies of thymoquinone and standard antibiotics against multi-drug resistant isolates
Ayed A. Dera, Irfan Ahmad, Prasanna Rajagopalan, Mesfer Al Shahrani, Ahmed Saif, Mohammad Y. Alshahrani, Yasser Alraey, Ahmad M. Alamri, Sultan Alasmari, Mohammed Makkawi, Ali G. Alkhathami, Gaffar Zaman, Abdulrahim Hakami, Razan Alhefzi, Mohammad A. Alfhili
Saudi Medical Journal Feb 2021, 42 (2) 196-204; DOI: 10.15537/smj.2021.2.25706
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Keywords

  • thymoquinone
  • antibacterial
  • adhesion
  • biofilm formation
  • synergism

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© 2021 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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