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Case ReportCase Report
Open Access

Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma

Ramy Samargandi, Mathilde Bernard, Elodie Miquelestorena-Standley and Louis Romée Le Nail
Saudi Medical Journal June 2024, 45 (6) 633-638; DOI: https://doi.org/10.15537/smj.2024.45.6.20230720
Ramy Samargandi
From the Department of Orthopedic Surgery and Traumatology (Samargandi, Bernard, Le Nail); from the Department of pathology (Miquelestorena-Standley), Tours Regional University Hospital, Tours, France, and from the Department of Orthopedic Surgery (Samargandi), Faculty of Medicine, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
MD
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  • ORCID record for Ramy Samargandi
  • For correspondence: [email protected]
Mathilde Bernard
From the Department of Orthopedic Surgery and Traumatology (Samargandi, Bernard, Le Nail); from the Department of pathology (Miquelestorena-Standley), Tours Regional University Hospital, Tours, France, and from the Department of Orthopedic Surgery (Samargandi), Faculty of Medicine, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
MD
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Elodie Miquelestorena-Standley
From the Department of Orthopedic Surgery and Traumatology (Samargandi, Bernard, Le Nail); from the Department of pathology (Miquelestorena-Standley), Tours Regional University Hospital, Tours, France, and from the Department of Orthopedic Surgery (Samargandi), Faculty of Medicine, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
MD
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Louis Romée Le Nail
From the Department of Orthopedic Surgery and Traumatology (Samargandi, Bernard, Le Nail); from the Department of pathology (Miquelestorena-Standley), Tours Regional University Hospital, Tours, France, and from the Department of Orthopedic Surgery (Samargandi), Faculty of Medicine, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
MD, PhD
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References

  1. 1.↵
    1. Amary F,
    2. Cleven AHG,
    3. Konishi E
    . Chondroblastoma. [Updated 2020; 2023 Sep 1]. Available from: https://publications.iarc.fr/Book-And-Report-Series/Who-Classification-Of-Tumours/Soft-Tissue-And-Bone-Tumours-2020
  2. 2.↵
    1. Laitinen MK,
    2. Stevenson JD,
    3. Evans S,
    4. Abudu A,
    5. Sumathi V,
    6. Jeys LM, et al.
    Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases. J Bone Oncol 2019; 17: 100248.
    OpenUrl
  3. 3.↵
    1. Ozkoc G,
    2. Gonlusen G,
    3. Ozalay M,
    4. Kayaselcuk F,
    5. Pourbagher A,
    6. Tandogan RN
    . Giant chondroblastoma of the scapula with pulmonary metastases. Skeletal Radiol 2006; 35: 42–48.
    OpenUrlCrossRefPubMedWeb of Science
  4. 4.↵
    1. Focaccia M,
    2. Gambarotti M,
    3. Hakim R,
    4. Paioli A,
    5. Cesari M,
    6. Spazzoli B, et al.
    Chondroblastoma’s lung metastases treated with denosumab in pediatric patient. Cancer Res Treat 2021; 53: 279–282.
    OpenUrl
  5. 5.↵
    1. Baumhoer D,
    2. Harder D,
    3. Ameline B,
    4. Dawson H,
    5. Kollar A
    . Metastasizing chondroblastoma: a rare bone tumor no longer supported by the WHO classification. Skeletal Radiol 2021; 50: 255–260.
    OpenUrl
  6. 6.↵
    1. Huang L,
    2. Cheng YY,
    3. Chow LT,
    4. Zheng MH,
    5. Kumta SM
    . Receptor activator of NF-kappaB ligand (RANKL) is expressed in chondroblastoma: possible involvement in osteoclastic giant cell recruitment. Mol Pathol 2003; 56: 116–120.
    OpenUrlAbstract/FREE Full Text
  7. 7.↵
    1. Won KY,
    2. Kalil RK,
    3. Kim YW,
    4. Park YK
    . RANK signalling in bone lesions with osteoclast-like giant cells. Pathology 2011; 43: 318–321.
    OpenUrlPubMed
  8. 8.↵
    1. Suster DI,
    2. Kurzawa P,
    3. Neyaz A,
    4. Jarzembowski JA,
    5. Lozano-Calderon S,
    6. Raskin K, et al.
    Chondroblastoma expresses RANKL by RNA in situ hybridization and may respond to denosumab therapy. Am J Surg Pathol 2020; 44: 1581–1590.
    OpenUrl
  9. 9.↵
    1. Calvert N,
    2. Wood D
    . Use of denosumab in recurrent chondroblastoma of the squamous temporal bone: a case report. Clin Case Rep 2017; 5: 411–413.
    OpenUrl
  10. 10.↵
    1. Visgauss JD,
    2. Lazarides A,
    3. Dickson B,
    4. Cardona D,
    5. Sheth M,
    6. DeWitt SB, et al.
    Treatment of chondroblastoma with denosumab: a case report with a correlative analysis of effect on the RANK signaling pathway. JBJS Case Connect 2021; 11.
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Saudi Medical Journal: 45 (6)
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Vol. 45, Issue 6
1 Jun 2024
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Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma
Ramy Samargandi, Mathilde Bernard, Elodie Miquelestorena-Standley, Louis Romée Le Nail
Saudi Medical Journal Jun 2024, 45 (6) 633-638; DOI: 10.15537/smj.2024.45.6.20230720

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Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma
Ramy Samargandi, Mathilde Bernard, Elodie Miquelestorena-Standley, Louis Romée Le Nail
Saudi Medical Journal Jun 2024, 45 (6) 633-638; DOI: 10.15537/smj.2024.45.6.20230720
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Keywords

  • chondroblastoma
  • bone tumors
  • metastasis
  • denosumab
  • RANK
  • RANK-L

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